A comparison of the effectiveness between amniotic membrane homogenate and transplanted amniotic membrane in healing corneal damage in a rabbit model |
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| Authors: | Qing Guo Jie Hao Qian Yang Linan Guan Shan Ouyang Jianwen Wang |
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| Affiliation: | 1. Department of Life Science and Engineering, Harbin Institute of Technology, Harbin, China;2. Department of Ophthalmology, The First Clinical Medical School of Harbin Medical University, Harbin, China |
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| Abstract: | Purpose: To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model. Method: The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group. Results: There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group. Conclusion: Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model. |
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| Keywords: | amnion amniotic membrane transplantation cornea corneal injury |
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