Pupillary responses in normal subjects following auditory stimulation |
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Authors: | T Hirano H Inoue T Uemura K Matsunaga |
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Institution: | 1.Department of Otorhinolaryngology, Faculty of Medicine,Kyushu University,Fukuoka,Japan;2.Department of Psychology, Faculty of Literature,Kyushu University,Fukuoka,Japan |
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Abstract: | To clarify pupillary responses of humans following auditory stimuli, we studied both eyes of 61 normal subjects using a computed pupillograph. Unilateral auditory stimulation elicited pupillary dilatation in all cases. Pupillary responses were classified according to duration as being either “long” or “short”. The duration of dilatation was 1530±320 ms (mean±SD) in the longlasting group (n=45) and 850±250 ms in the short-lasting group (n=16). The latency time for dilatation was 460±80 ms. Both eyes of each subject showed the same response. Two drops of 10% guanethidine, a sympathetic blocking agent, were applied to one eye of 3 subjects. Although the early phase of dilatation was barely affected, the late phase was inhibited, as seen in long-lasting dilatation. The short-lasting response was unaffected. We conclude that the long-lasting response consists of an early pupillary dilatation due to inhibition of parasympathetic nervous activity and a late dilatation due to excitation of sympathetic activity. The short-lasting response is produced only by inhibition of the parasympathetic component. |
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