| 脑梗死患者治疗前后血清GM-CSF和PGMP测定的临床意义 |
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| 引用本文： | 臧志忠,潘生英,唐勇,王军.脑梗死患者治疗前后血清GM-CSF和PGMP测定的临床意义[J].放射免疫学杂志,2006,19(6):475-476. |
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| 作者姓名： | 臧志忠 潘生英 唐勇 王军 |
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| 作者单位： | 江苏省丹阳市人民医院神经内科,212300;南京市第一人民医院神经内科,210006 |
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| 摘 要： | 目的：探讨了脑梗死患者治疗前后血清GM—CSF和血小板α-颗粒膜蛋白（PGMP）水平的变化及意义。方法：应用放射免疫分析对36例脑梗死患者进行了血清GM—CSF和PGMP水平测定，并以30例正常健康人作比较。结果：在治疗前血清GM—CSF和PGMP水平均非常显著地高于正常人组（P〈0．01），经治疗后6个月与正常人比较仍有显著差异（P〈0．05）。结论：脑梗死的发生、发展与血清GM—CSF和PGMP水平密切相关。
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| 关 键 词： | 脑梗死 粒细胞巨噬细胞-集落刺激因子 血小板α-颗粒膜蛋白 |
| 收稿时间： | 2006-08-24 |
| 修稿时间： | 2006年8月24日 |
Clinical Significance of Determination of Changes of Serum GM-CSF and Platelet Granular Membrance Protein (PGMP) Contents After Treatment in Patients with Cerebral Infarction |
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| Zang Zhizhong, et al.Clinical Significance of Determination of Changes of Serum GM-CSF and Platelet Granular Membrance Protein (PGMP) Contents After Treatment in Patients with Cerebral Infarction[J].Journal of Radioimmanology,2006,19(6):475-476. |
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| Authors: | Zang Zhizhong |
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| Abstract: | Objective To investigate the changes of serum GM-CSF and PGMP levels after treatment in patients with cerebral infarction.Methods Serum GM-CSF and PGMP contents were measured with RIA in 36 patients with cerebral infarction both beforeand after treatment as well as in 30 controls.Results Before treatment,the serum GM-CSF and PGMP levels in the patients were significantly higher than those in the controls(P<0.01).After 6 months' treatment,the levels(though dropped markedly),remained significantly higher(P<0.05).Conclusion Serum GM-CSF and PGMP levels might be of prognostic value in patients with cerebral infarction. |
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| Keywords: | cerebral infarction granulocyte-macrophage colony stimulating factor(GM-CSF) platelet granular membrance protein(PGMP) |
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