The use of indigocarmine spray increases the colonoscopic detection rate of adenomas |
| |
Authors: | Kazutomo Togashi David G Hewett Graham L Radford-Smith Leo Francis Barbara A Leggett Mark N Appleyard |
| |
Institution: | (1) Department of Gastroenterology and Hepatology, Royal Brisbane and Women’s Hospital, Level 9 Ned Hanlon Building, Herston, QLD, 4029, Australia;(2) Department of Anatomical Pathology, Royal Brisbane and Women’s Hospital, Herston, QLD, 4029, Australia;(3) Department of Endoscopy and Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke Tochigi, 329-0498, Japan |
| |
Abstract: | Purpose It remains controversial whether chromocolonoscopy using indigocarmine increases the detection of colorectal polyps. We aimed
to assess the impact of indigocarmine dye spray on the detection rate of adenomas and the feasibility of learning the technique
in a Western practice.
Methods 400 patients were prospectively allocated into 2 groups; A (n = 200): indigocarmine chromocolonoscopy was performed by a Japanese colonoscopist with expertise in chromoscopy; B (n = 200): initial 100 patients (B-1), a Western colonoscopist with no previous experience of chromoscopy performed conventional
colonoscopy, but with at least 10 min observation during colonoscopy withdrawal. In the next 100 patients (B-2), he performed
chromocolonoscopy. All polyps found were resected. Regression analysis was used to compare the numbers of polyps detected
in groups A, B-1 and B-2, whilst controlling for gender, age, indication and history of colorectal cancer.
Results There were significant differences in the numbers of neoplastic polyps and flat adenomas between groups A and B-1 as well
as between B-1 and B-2, but not between A and B-2. There was no significant difference in numbers of advanced lesions. Chromocolonoscopy
(A and B-2) detected more neoplastic polyps of ≤5 mm.
Conclusion Chromocolonoscopy increases the detection of neoplastic polyps and flat adenomas, particularly diminutive polyps, but does
not increase the detection of advanced lesions. |
| |
Keywords: | Colonoscopy Chromoendoscopy Indigocarmine Colon polyp |
本文献已被 SpringerLink 等数据库收录! |
|