盐酸曲唑酮治疗勃起功能障碍的随机对照研究

目的　为了观察盐酸曲唑酮治疗阴茎勃起障碍的疗效和安全性。方法　入选 6 5例轻、中度阴茎勃起功能障碍 (ED)患者 ,随机分 2组 :盐酸曲唑酮组 5 0mg每日一次口服 ,逐日增加至 15 0mg后维持 ;对照组给安慰剂。治疗前与治疗后 4周 ,以勃起功能国际指标评分问卷 (IIEF 5 )得分之和作为判断标准。结果　显效 3例(10 % ) ,有效 9例 (30 % ) ,总有效率为 4 0 % ,无效 18例 (6 0例 ) ;对照组有效 6例 (16 .7% ) ,曲唑酮组治疗前后比较差异有显著性 (P <0 .0 5 )。副作用为头晕、嗜睡。结论　本研究初步证明曲唑酮治疗轻、中度勃起功能障碍有一定疗效

Randomly study on erectile dysfunction treated by trazodone

Objective To observe the efficacy and tolerance of Trazodone in Treating erectile dysfunction (ED).Methods 65 patients were randomly assigned into two groups.Patients in Trazodone group were treated with trazodone from 50 mg a day gradually increased 150 mg a day over 4 weeks.Patients in control group were given placebo.The IIEF?5 was used to evaluate the effects before and after interference.Results the effective rates were 40%,while the response rates of control group were 16.7%.There was significant difference in trazodone group before and after treatment.The side effects were slight dizziness,fatigue and sleepness.Conclusions Administration of Trazodone significantly improved the sexual function in patients suffered from mild and moderate ED.