丙泊酚复合雷米芬太尼麻醉时不同脑电双频指数对斜视矫正术眼心反射的影响

目的观察丙泊酚复合雷米芬太尼麻醉时不同脑电双频指数(BIS)下眼心反射发生情况。方法2~12岁择期行斜视矫正术患儿63例均分为P1、P2和P3三组,输注雷米芬太尼12μg.kg-1.h-1和丙泊酚3~7 mg.kg-1.h-1麻醉。术中调节丙泊酚输注速度,使BIS维持于60(P1组)、50(P2组)和40(P3组)。记录麻醉前和术中牵拉眼肌时的HR和眼心反射发生率。结果P1、P2和P3组眼心反射发生率分别为66.7%、33.3%和9.5%,P2、P3组明显低于P1组(P0.01)。结论麻醉时维持BIS在40~50时,眼心反射发生率较低。

Effect of BIS on the incidence of oculocardiac reflex during propofol-remifentanil anaesthesia in paediatric strabismus surgery

Objective To evaluate the effect of bispectral index(BIS) on the incidence of oculocardiac reflex(OCR) during propofol-remifentanil anaesthesia in paediatric strabismus surgery. Methods Sixty-three patients (2-12 years older) undergoing strabismus surgery were randomly allocated to three groups with 21 cases each. Anesthesia was maintained with infusion of remifentanil 12 μg·kg~(-1)·h~(-1) and proporol 3-7 mg·kg~(-1)·h~(-1). The target BIS values of 60(group P_1), 50(group P_2) and 40(group P_3) were kept by regulating the infusion rate of propofol. The incidence of OCR and heart rate during operation were recorded. Results The incidences of OCR in groups of P_1, P_2 and P_3 were 66. 7%,33. 3% and 9. 5%,respectively(P<0.01). Conclusion The incidence of OCR can be reduced when BIS is kept in 40-50 in children undergoing strabismus surgery under propofol-remifentanil anesthesia.