温针灸、浮针及针刺治疗膝骨性关节炎临床研究

目的:研究温针灸、浮针及针刺治疗膝骨性关节炎(KOA)的临床疗效。方法:选取80例KOA患者为对象,采用随机数字法将其分为对照组(n=40)和观察组(n=40),对照组给予金骨莲胶囊联合塞来昔布胶囊治疗,观察组给予温针灸、浮针及针刺治疗,比较两组临床疗效、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分、膝关节功能(KSS)评分、血清炎性因子C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)]水平及不良反应发生率。结果:观察组治疗有效率高于对照组(95.00%与77.50%)(P<0.05); 治疗后观察组疼痛、僵硬及日常活动评分均显著低于对照组(P<0.05); 治疗后观察组KSS评分高于对照组(P<0.05); 治疗后观察组血清CRP、TNF-α、IL-6水平均低于对照组(P<0.05); 观察组不良反应发生率0%低于对照组12.50%(P<0.05)。结论:温针灸、浮针及针刺治疗KOA临床疗效显著,可缓解临床症状,提高膝关节功能评分,降低炎性因子水平,且安全性较高。

Clinical study on the treatment of knee osteoarthritis with warm acupuncture,floating needle and acupuncture

Objective:To study the clinical effect of warm acupuncture,floating needle and acupuncture on knee osteoarthritis(KOA).Methods: Eighty cases of KOA patients were selected as the object.They were divided into the control group(n=40)and the observation group(n=40).The control group was treated with jingulian capsule combined with celecoxib capsule.Clinical efficacy,WOMAC score,knee joint function(KSS)score,serum inflammatory factors C-reactive protein(CRP),Tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)] and incidence of adverse reactions were compared between the two groups.Results:The effective rate of the observation group was higher than that of the control group(95.00% vs 77.50%)(P<0.05).After treatment,the pain,stiffness and daily activity scores of the observation group were significantly lower than those of the control group(P<0.05).KSS score of the observation group was higher than that of the control group after treatment(P<0.05).After treatment,serum CRP,TNF-level and il-6 levels in the observation group were lower than those in the control group(P<0.05).The incidence of adverse reactions in the observation group 12.50% was lower than that in the control group 0%(P<0.05).Conclusion:The clinical efficacy of warm acupuncture,floating acupuncture and acupuncture on KOA is significant,which can relieve the clinical symptoms,improve the knee function score,reduce the level of inflammatory factors,and is of high safety.