黄芪汤加减治疗溃脓期肺痈临床观察

目的:探讨验方黄芪汤内服治疗溃脓期肺痈的临床疗效及其作用机制。方法:采用随机分组法将病例各分为治疗组(20例)与对照组(20例),治疗组用黄芪汤,用法:将药煎取400 ml,分早中晚饭后温服,1周为1个疗程,连用1月;对照组西医西药治疗方案选择单用足量敏感抗生素静滴,每天两次,连用1月;1月后复查X线胸片、胸部CT或MRI、支气管镜检查、痰或血培养、血常规等指标。将搜集的资料进行统计学处理。结果:治疗组能明显改善咳嗽、咳痰、胸痛、高热、畏寒、心悸、气短、纳差、乏力等全部证候(P<0.05),总有效率为95.00%,对照组能改善咳嗽、咳痰、胸痛、高热、畏寒等证候(P<0.05),总有效率为70.00%,两组治疗后在咳嗽、咳痰、胸痛、畏寒、纳差、乏力等证候评分上组间比较差异具有统计学意义(P<0.05),治疗组优于对照组。影像学指标,两组治疗后均能明显改善X线胸片、胸部CT及MRI等影像学指标(P<0.05),组间比较差异具有统计学意义(P<0.05);对于支气管镜像,两组患者治疗后都能降低支气管黏膜损害程度、炎症程度,提高管壁运动状态,组间比较差异具有统计学...

Clinical observation of Huangqi decoction in the treatment of pulmonary carbuncle in purulent period

Objective:To investigate the clinical efficacy and mechanism of Huangqi decoction in the treatment of pulmonary carbuncle in ulcerative stage.Methods:The cases were randomly divided into treatment group(20 cases)and control group(20 cases).The treatment group was treated with Huangqi decoction.Usage:decoct 400 ml of medicine and took it warm after breakfast,lunch and dinner,one week as a course of treatment,for one month.The control group was treated with western medicine by intravenous drip of sufficiently sensitive antibiotics,twice a day,for one month.Chest X-ray,chest CT or MRI,bronchoscopy,sputum or blood culture,blood routine and other indicators were re-examined after 1 month.The collected data were processed by statistics.Results:The treatment group could obviously improve all the symptoms of cough,sputum,chest pain,high fever,chills,palpitations,shortness of breath,poor appetite and fatigue(P<0.05).The total effective rate was 95.00%.The control group could improve the symptoms of cough,sputum,chest pain,high fever and chills(P<0.05).The total effective rate was 70.00%.After treatment,cough,palpitation,shortness of breath,poor appetite and fatigue were improved in both groups.There were significant differences in the scores of cough,chest pain,chills,poor appetite and fatigue between the two groups(P<0.05).The treatment group was better than the control group.For imaging indicators,the treatment group and the control group is a significant difference between the two groups(P<0.05);for bronchoscopy,the two groups can significantly improve X-ray chest film,chest CT and MR imaging indicators(P<0.05),can reduce the degree of bronchial mucosal damage and inflammation after treatment.There was significant difference between the two groups in improving wall motion(P<0.05),and the treatment group was better than the control group(P<0.05);There was no significant difference in the degree of lumen stenosis between the two groups before and after treatment(P>0.05).Conclusion:Huangqi decoction can obviously relieve the clinical symptoms of pulmonary carbuncle in purulent ulcer stage and improve the corresponding laboratory examination indicators,which is worthy of clinical application.