| 木糖醇注射液有关物质的薄层色谱研究 |
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| 引用本文： | 苏小兰,梁懿.木糖醇注射液有关物质的薄层色谱研究[J].亚太传统医药,2012,8(10):34-35. |
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| 作者姓名： | 苏小兰 梁懿 |
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| 作者单位： | 南宁百会药业集团有限公司,广西南宁,530005 |
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| 摘 要： | 目的:建立木糖醇注射液中有关物质的薄层鉴别方法。方法:采用薄层色谱法对木糖醇注射液中的有关物质进行定性鉴别。结果:缺木糖醇的阴性对照样品无干扰;最小检测限为2μg;高温、酸破坏和碱破坏条件下稳定,在氧化条件下不稳定,易发生降解,重现性良好。结论:该方法专属性强,能将破坏性试验中的降解产物与主斑点分离,可用于木糖醇注射液有关物质的控制。
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| 关 键 词： | 木糖醇注射液 薄层色谱法 薄层鉴别 |
Study on the TLC Method of Related Substance in Xylitol Injection |
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| Su Xiaolan
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Liang Yi.Study on the TLC Method of Related Substance in Xylitol Injection[J].Asia-Pacific Traditional Medicine,2012,8(10):34-35. |
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| Authors: | Su Xiaolan Liang Yi |
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| Institution: | (Guangxi Nanning Bestway Pharmaceutical Co. Ltd. , Nanning 530005 ,China) |
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| Abstract: | Objective：To establish TLC Method for Xylitol injection. Methods：Qualitative identification was adopted in the TLC method of related substance in the Xylitol injection. Results：No interference was detected in negative control sample; detection limit is 2.0μg, the method is stable in high temperature and alkali destroyed conditions, unstable and easy to degrade under Oxidation cir- cumstance, repeatability is good respectively. Conclusion： The method is specific and able to separate the Destructive testing degra- dation with the main spot, can be used as the control method for related substance in xylitol injection. |
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| Keywords: | Xylitol Injection TCL Related Substance |
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