| 硒氟联合作用对雄性大鼠生殖毒性的影响 |
| |
| 引用本文： | 王爱国,杨克敌.硒氟联合作用对雄性大鼠生殖毒性的影响[J].中国地方病学杂志,1996,15(4):202-204. |
| |
| 作者姓名： | 王爱国 杨克敌 |
| |
| 作者单位： | 武汉同济医科大学环境卫生学教研室 |
| |
| 摘 要： | 通过饮水加氟、加硒的方法，观察氟、硒对大鼠精了形态学指标的影响。结果表明，氟可使大鼠精数目减少，精子活动率和活动度降低，精子畸形率升高，给氟同时给予硒，则可以拮抗氟的这种作用。说明氟对大鼠存在的生殖毒性，而加硒则可以拮抗氟的生殖毒性。
|
| 关 键 词： | 氟 硒 毒性 生殖毒性 大鼠 |
Combined effect of Selenium and Fluoride on reproductive toxicity in male rats |
| |
| Wang Aiguo,Yang Kedi,Li Xianxiang,Wang Guizhen,Liu Sihai.Combined effect of Selenium and Fluoride on reproductive toxicity in male rats[J].Chinese Jouranl of Endemiology,1996,15(4):202-204. |
| |
| Authors: | Wang Aiguo Yang Kedi Li Xianxiang Wang Guizhen Liu Sihai |
| |
| Institution: | Wang Aiguo,Yang Kedi,Li Xianxiang,Wang Guizhen,Liu Sihai Department of Environmental health,Tongji Medical University,Wuhan,430030 |
| |
| Abstract: | Sodium fluoride and sodium selenite in deionized water were administered to male rats for 8 weeks. The count, mobility and morphological change of sperm were observed. The present results showed that NaF could reduce the sperm count and sperm mobility, and increase the abnormal sperm significantly. It was found that combined administration of fluoride and selenium to male rats could decrease this kind of effect of fluoride. Thus, it could be concluded that fluoride can cause the reproductive toxicity in male rats, indeed, whereas selenium can antagonize with the reproductive toxicity of fluoride. |
| |
| Keywords: | Fluoride Selenium Reprodective toxicity Male rats |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
