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ACE基因多态性与急性缺血性中风始发证候相关性的研究
引用本文:贾妮,尤劲松,黄培新. ACE基因多态性与急性缺血性中风始发证候相关性的研究[J]. 辽宁中医杂志, 2008, 35(4): 481-483
作者姓名:贾妮  尤劲松  黄培新
作者单位:广东省中医院,广东,广州,510120;广东省中医院,广东,广州,510120;广东省中医院,广东,广州,510120
摘    要:目的:探讨ACE基因多态性与急性缺血性中风始发证候的相关性。方法:选择发病7天之内急性缺血性中风患者118例,进行ACE基因(D/I)多态性检测,同时进行证候分型,分析两者之间的相关性。结果:单因素分析结果显示,非II型痰证比例明显升高,χ2=4.882,P=0.036;非DD型气虚证比例明显升高,χ2=4.750,P=0.036;组间比较有统计学意义。结论:D等位基因与痰证、I等位基因与气虚证的发生可能存在相关性。

关 键 词:ACE基因多态性  急性缺血性中风  始发证候
文章编号:1000-1719(2008)04-0481-03
修稿时间:2007-11-25

Exploration on the Relevance of the ACE Gene Polyrnorphism and Acute Ischemic Stroke Predicate Syndrome
JIA Ni,YOU Jin-song,HUANG Pei-xin. Exploration on the Relevance of the ACE Gene Polyrnorphism and Acute Ischemic Stroke Predicate Syndrome[J]. Liaoning Journal of Traditional Chinese Medicine, 2008, 35(4): 481-483
Authors:JIA Ni  YOU Jin-song  HUANG Pei-xin
Abstract:Objective:Explore the ACE gene polymorphism and acute ischemic stroke predicate syndrome relevance.Methods:The incidence within seven days of acute ischemic stroke patients with 118 cases,the ACE gene(I / D) polymorphism detection,simultaneously syndrome typing,analysis between the two relevant.Results: Univariate analysis showed that non-certified Type II sputum ratio increased significantly,χ2 = 4.882,P = 0.036;Non-DD-deficiency syndromes ratio increased significantly,χ2 = 4.750,P=0.036;Differences between the groups was statistically significance.Conclusion :D allele and sputum card,I allele and the incidence of deficiency syndromes possible relevance.
Keywords:ACE gene polymorphism  acute ischemic stroke  predicate syndrome
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