参附注射液对单次脊麻手术患者血流动力学的影响

目的：观察参附注射液预注对单次脊麻手术患者血流动力学的影响。方法：90例单次脊麻手术患者随机分为参附组（A）和对照组（B）,每组45例。A组麻醉前输注乳酸钠林格液500mL＋参附注射液50mL,B组输注乳酸钠林格液500ml。观察两组患者收缩压（SBP）、舒张压（DBP）、心率（HR）、血氧饱和度（SPO2）的变化。记录血管活性药物麻黄碱,阿托品的使用例数。结果：A组给局麻药后5min,15min SBP,DBP明显高于B组（P〈0.05）,注药后15min HR明显高于B组（P〈0.05）。A组血管活性药物使用例数显著低于B组（P〈0.05）。结论：参附注射液预注应用于单次脊麻手术患者,可降低心动过缓和低血压发生率,对血流动力学稳定有保护作用。

Effects of Shenfu Injection on Hemodynamics Undergoing Spinal Anesthesia

Objection：Serving the effects of shenfu pre-injection on hemodynamics in patients undergoing single spinal anesthesia.Methods：ninety patients who scheduled for abdominal or lower limb operation were randomly divided into two groups with 45 cases each group.Group A were injected 50ml Shenfu dissolved in 500mL Sodium dissolved in 500mL sodium lactate ringer injection before anesthesia.And group B were only injected 500mL sodium lactate ringer injection.The following data were recorded and analyzed：SBP、 DBP、 HR、 SPO2 and the cases of using ephedrine and atropine.Results：Compared with group B,SBP and DBP were obviously increased in 5 minutes and 10 minutes after anesthesia in group A（P〈0.05）;HR was obviously increased in 15 minutes（P〈0.05）.The cases of using ephedrine and atropine were obviously decreased in group A（P〈0.05）than group B.Conclusion：Pre-injection shenfu is useful in maintaining stability of hemodynamic in patients during single spinal anesthesia,which could decrease the incidence of hypotension and bradycardia.