| 高血压病人纤维蛋白原水平及纤溶系统功能研究 |
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| 引用本文： | 陈红.高血压病人纤维蛋白原水平及纤溶系统功能研究[J].心肺血管病杂志,1999,0(1):16-17. |
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| 作者姓名： | 陈红 |
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| 作者单位： | 北京医科大学人民医院,100044,心内科 |
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| 摘 要： | 为了解高血压病人的血栓形成倾向，我们随机选取了４１例高血压病人及３４例正常血压者，分别观察了他们的纤维蛋白原及血浆组织型纤溶酶原激活物（ｔＰＡ）抗原及纤溶酶原激活物抑制物－１（ＰＡＩ－１）的含量。结果表明，高血压病人血浆纤维蛋白原水平无明显变化，但ｔＰＡ抗原含量减少，ＰＡＩ－１的水平增加。提示高血压病人存在内源性纤溶功能受损
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| 关 键 词： | 高血压病 纤维蛋白原 组织型纤溶酶原激活物 纤溶酶原激活物抑制剂 |
Plasma Level of Fibrinogen and Fibrinolysis in Essential Hypertension Patients |
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| Chen Hong.Plasma Level of Fibrinogen and Fibrinolysis in Essential Hypertension Patients[J].Journal of Cardiovascular and Pulmonary Diseases,1999,0(1):16-17. |
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| Authors: | Chen Hong |
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| Abstract: | In order to study the ability to the thrombus formation,41 patients with essential hypertension and 34 patients with normotension were investigated.The plasma level of fibrinogen and tissue-type plasminogen activator(tPA) antigen and plasminogen activator inhibitor 1(PAI-1)antigen were determined.In comparing with normotensive subjects,essential hypertensive patients had higher plasma concentration of PAI-1 antigen(P>0.05)and lower plasma level of tPA antigen (P<0.05),but similar plasma level of fibrinogen(P>0.05).The results suggest that there is impaired fibrinolysis in patients with hypertension. |
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| Keywords: | Essential hypertension \ Fibrinogen \ Tissue-type plasminogen activator \ Plasminogen activator inhibitor 1 |
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