Subtyping of human immunodeficiency virus type 1 strains by using antibodies specific for the third variable domain (V3) of gp120: results may be affected by divergent V3 sequences. |
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| Authors: | K Sherefa, M S llberg, B Johansson, M Salminen, A S nnerborg |
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| Affiliation: | K Sherefa, M Sällberg, B Johansson, M Salminen, and A Sönnerborg |
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| Abstract: | Human immunodeficiency virus type 1 serotype C was found in 545 of 712 Ethiopian patients by peptide enzyme immunoassay. Serotyping failed in 146 samples due to the absence of V3 antibodies or multiple reactivities. In 6 of 34 samples, discordant results were obtained by serotyping and genotyping, possibly due to divergent V3 sequences. |
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