三种不同术式翼状胬肉切除术的临床对比观察

目的观察丝裂霉素C（MMC）或羊膜移植在翼状胬肉切除术中应用的临床疗效。方法对临床收治的需行翼状胬肉切除术病例随机分为3组进行手术。A组为单纯翼状胬肉切除;B组为翼状胬肉切除联合应用MMC,术中于翼状胬肉切除区巩膜面及结膜下放置0.4 mg/ml MMC 3 min;C组为翼状胬肉切除联合生物羊膜移植,于翼状胬肉切除区巩膜面植入瑞济干燥羊膜植片。术后1周、2周、1个月、3个月、1年、2年检查记录术眼并发症及复发情况。结果随访观察6个月至3年,A组60例（68只眼中）22只眼复发（32.4%）;B组60例（72只眼）中12只眼复发（16.7%）;C组50例（60只眼）中5只眼复发（8.3%）。A组与B组比较、A组与C组比较（P〈0.05）,差异具有显著性;B组与C组比较（P〉0.05）,复发率无显著性差异。结论翼状胬肉切除联合丝裂霉素C或生物羊膜移植手术、手术安全、可以减少翼状胬肉切除术后复发率。

Comparison of three different surgical excision of pterygium

Objective To observe the clinical efficacy of mitomycin C or amniotic membrane ransplantation for pterygium excision in the pplication.Methods Of clinical needs were treated cases of pterygium excision surgery were randomly divided into 3 groups,group A for the simple pterygium excision.group B pterygium excision combined with mitomycin C.Pterygium surgery on scleral surface area and placed under the conjunctiva 0.4 mg/ml MMC 3 min.Pterygium excision with group C,amniotic membrane transplantation.Sclera pterygium excision area in the implant surface dried amniotic membrane grafts of Ruiji.1 week,2 weeks,1 month,3 months,1 year,2 years inspection records eye surgery lications and recurrence.Results Followed up for 6 months-3 years,group A of 68 eyes of 22 recurrence（32.4%）;group B 72 eyes of 12 recurrences（16.67%）;group C of 60 eyes of 5 recurrences（8.3%）.Group A and group B,group A and group C（P0.05）,differences were significant;group B and group C（P0.05）,relapse rate was no significant difference.Conclusion Pterygium excision combined with mitomycin C or amniotic membrane transplantation,surgical safety,can reduce the recurrence rate after pterygium xcision.