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抗抑郁治疗对老年高血压降压疗效的影响
引用本文:李卫媛,阮丽波.抗抑郁治疗对老年高血压降压疗效的影响[J].临床心血管病杂志,2011,27(4).
作者姓名:李卫媛  阮丽波
作者单位:云南省第一人民医院老年病科,昆明,650032
摘    要:目的:探讨抗抑郁治疗对老年高血压患者降压疗效的影响.方法:观察85例老年高血压合并抑郁症状的患者随机分为2组,所有患者均给予钙拮抗剂(氨氯地平5 mg/d)、血管紧张素转化酶抑制剂(贝那普利10 mg/d),抗抑郁治疗组在此基础上加用帕罗西丁20 mg/d.结果:抗抑郁治疗组其降压幅度,降压有效率,汉密尔顿抑郁量减分率均优于治疗前及对照组,差异显著有统计学意义(P<0.05).结论:抗抑郁治疗可增强老年高血压合并抑郁患者的降压效果.

关 键 词:高血压  抑郁  帕罗西丁

The effects of antidepressant treatment on antihypertensive therapy in elderly patients
LI Weiyuan,RUAN Libo.The effects of antidepressant treatment on antihypertensive therapy in elderly patients[J].Journal of Clinical Cardiology,2011,27(4).
Authors:LI Weiyuan  RUAN Libo
Institution:LI Weiyuan RUAN Libo(Department of Gerontology,the first people's hospital of Yunnan province,Kunming 650032,China)
Abstract:Objective:To explore the effects of antidepressant treatment on antihypertensive therapy of elderly patients.Method:85 senile hypertensive patients with depression were randomly divided into A and B,two groups for study.Then 5 mg/d Amlidipine and 10 mg/d Benazepril were orally administrated to each group as basic antihypertensive medication.Besides,20 mg/d paroxetine was additionally given to group A.Result:Group A shows its patients' blood pressure of average reduction,effective rate of blood pressure redu...
Keywords:hypertension  depression  paroxetine  
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