CGMS与CSII联合强化治疗危重症老年2型糖尿病疗效观察

目的：对动态血糖监测系统（continuous glucose monitoringsystem，CGMS）与胰岛素泵持续皮下输注胰岛素（continuous subcutaneous insulininfusion，CSII）联合治疗危重症老年2型糖尿病（T2DM）（联合组）的效果进行观察，并与多次皮下注射胰岛素（multiple daily insulin injection，MDII）组进行比较。方法：合并危重症的老年T2DM患者39例，随机为联合组（n=19）及MDII组（n=20），比较两组每日使用胰岛素量、平均血糖漂移幅度（mean amplitude of glycemic excursions，MAGE）、血糖达标天数、低血糖发生率、多脏器功能不全综合征（MODs）发生率及死亡率的差异。结果：联合组胰岛素用量、低血糖发生率、血糖达标天数、MODs发生率低于MDII组（P〈0．01或P〈0．05）。结论：CGMS与CSII联合治疗相较于MDII，可以更平稳、迅速的控制危重症老年T2DM患者的血糖，降低其并发症发生率。

CGMS plus CSII in Intensive Therapy of Senile Patients with Critical Type 2 Diabetic Patients with Critical Illness

Objective：To observe the curative effects of CGMS plus CSII in intensive therapy of senile patients with critical type 2 diabetic. Method：The 39 senile patients with critical type 2 diabetic were randomly divided into two groups. CGMS plus CSII （Combination） group （n= 19） and MDII group （n = 20）, the dosage of required insulin per day, MAGE, the required days of reach mark glucose ,the frequency of hypoglycemia, the frequency of MODS and the mortality were compared in the two groups. Result：The dosage of required insulin per day, MAGE, the required days of reach mark glucose, the frequency of hypoglycemia, the frequency of MODS was lower in Double C group. Conclusion：Satis factory effects can be expected in intensive treating the senile patients with critical type 2 diabetic with CGMS plus CSII.