骨髓活检同步观察在全血细胞减少症中的诊断价值

目的探讨骨髓活检与骨髓涂片同步观察对全血细胞减少症诊断的意义。方法对我院289例全血细胞减少症患者,采用骨髓穿刺、活检双标本一步法取材,同时观察其骨髓涂片和骨髓活检塑料包埋切片。结果诊断以再生障碍性贫血（AA）和骨髓增生异常综合征（MDS）为多见,占60.90%（176/289）;其次为白血病、增生性贫血、骨髓纤维化等,在疾病诊断方面,骨髓活检优于涂片。结论骨髓活检能更全面地衡量造血细胞增生程度;骨髓活检与涂片同步观察能有效提高全血细胞减少症的诊断准确率。

Diagnosis value of synchronism marrow biopsy and bone marrow smear on pancytopenia

Objective To study the diagnostic value of synchronism marrow biopsy and bone marrow smear on pancytopenia. Methods The marrow samples of 289 patients with pancytopenia were collected, including bone marrow biopsy and bone marrow smear. Those sections and smears were observed. Results Of 289 patients, there were 176 patients diagnosed as aplastic anemia （AA） and myelodysplastic syndrome（MDS）. Bone marrow smear was more valuable than bone marrow biopsy in diagnostic value. Conclusion Bone marrow biopsy can measure the hyperplasia level of the hematopoietic cells overall. The synchronism observation on both marrow biopsy and marrow smear can increase the diagnosis rate, effectively.