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恶性淋巴瘤中医病机与治疗
引用本文:王双双,胡兵,安红梅.恶性淋巴瘤中医病机与治疗[J].世界科学技术-中医药现代化,2014,16(11):2425-2429.
作者姓名:王双双  胡兵  安红梅
作者单位:上海中医药大学附属龙华医院/中医肿瘤研究所 上海 200032
基金项目:国家自然科学基金委面上项目(81273726):藤龙补中汤对大肠癌细胞衰老作用表观遗传机制研究,负责人:胡兵;上海市卫生和计划生育委员会上海市中医药事业三年行动计划首批重大研究项目(ZYSNXD-CC-ZDYJ017):肿瘤生物学与抗癌中药作用机制及配伍,负责人:胡兵;上海中医药大学杏林学者项目及龙华医院国家中医临床研究基地“龙医团队、龙医学者”项目(LYTD-04),负责人:胡兵。
摘    要:恶性淋巴瘤是一种常见的恶性肿瘤,其中医病因病机涉及湿、痰、毒、瘀、虚。辨证论治与扶正祛邪是淋巴瘤中医治疗基本原则,利湿、化痰、解毒、化瘀、扶正是淋巴瘤的重要治法。当代中医发展了益化汤、紫牛散、克瘤胶囊、吴氏消瘤散等淋巴瘤治疗复方,以及淋巴瘤中医药治疗专利37项。中医药治疗淋巴瘤作用机制涉及抑制细胞增殖、诱导细胞凋亡、抑制血管生成及免疫调节等方面。研究淋巴瘤细胞特异中医药治疗具有重要意义。

关 键 词:恶性淋巴瘤  中医药  病因病机  治疗  作用机制  细胞与分子生物学
收稿时间:5/7/2014 12:00:00 AM
修稿时间:2014/6/30 0:00:00

Traditional Chinese Medicine Pathogenesis and Treatment of Malignant Lymphoma
Wang Shuangshuang,Hu Bing and An Hongmei.Traditional Chinese Medicine Pathogenesis and Treatment of Malignant Lymphoma[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2014,16(11):2425-2429.
Authors:Wang Shuangshuang  Hu Bing and An Hongmei
Institution:Department of Oncology / Institute of Traditional Chinese Medicine in Oncology, Longhua Hos pital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
Abstract:Malignant lymphoma is a common malignancy. From the perspective of the traditional Chinese medicine (TCM), the etiology and pathogenesis of malignant lymphoma are related to dampness, phlegm, toxicity, stasis and deficiency. Basic TCM principles for lymphoma syndrome differentiation and treatment are to strengthen the body resistance and eliminate pathogenic factors. Eliminating dampness, dissolving phlegm, detoxification, dissolving stasis and strengthening body resistance are the principal TCM therapeutic methods for lymphoma treatment. Contemporary TCM physicians have developed Yi-Hua decoction, Zi-Niu powder, Ke-Liu capsule, Wu's Xiao-Liu powder and other herbal formulas, and 37 patents based on Chinese herbs and or herbal components. The effective mechanisms of TCM treatment for lymphoma are involved in inhibiting proliferation, inducing apoptosis, inhibiting angiogenesis, and regulating immune function. There is a great need to study anti-cancer herbs for lymphoma treatment.
Keywords:Malignant lymphoma  traditional Chinese medicine  etiology and pathogenesis  treatment  effective mechanism  cellular and molecular biology
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