Bacteremia and infective endocarditis caused by a non-daptomycin-susceptible, vancomycin-intermediate, and methicillin-resistant Staphylococcus aureus strain in Taiwan |
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| Authors: | Huang Yu-Tsung Hsiao Cheng-Hsiang Liao Chun-Hsing Lee Chung-Wei Hsueh Po-Ren |
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| Affiliation: | Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei County, Taiwan,1 Departments of Internal Medicine,2 Pathology,3 Radiology,4 Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan5 |
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| Abstract: | We describe the development of nonsusceptibility to daptomycin and vancomycin during treatment for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia associated with infective endocarditis and probable septic thrombophlebitis in a uremic patient. MRSA bacteremia persisted during glycopeptide and subsequent daptomycin treatment but cleared after 5 days' treatment with linezolid and fusidic acid. |
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