两种方案治疗单纯性收缩期高血压的成本-效果分析

目的比较厄贝沙坦与硝苯地平缓释片或氢氯噻嗪片联合治疗单纯性收缩期高血压的经济效果。方法将240例单纯性收缩期高血压患者随机分成2组,A组采用厄贝沙坦片和硝苯地平缓释片联合治疗,B组采用厄贝沙坦片和氢氢噻嗪片联合治疗,并采用药物经济学原理对2种治疗方案进行成本—效果分析。结果A、B组的总有效率分别为95%、90%,成本效果比分别为4.23、3.78。两组方案的总有效率无显著性差异,而B组的成本效果比明显小于A组。结论综合考虑,厄贝沙坦片与氢氯噻嗪片联合应用是治疗单纯性收缩期高血压的最佳方案。

Cost-effectiveness Analysis of Two Schemes in the Treatment of Pure Systolic Hypertension

OBJECTIVE To compare the cost-effectiveness between Irbesartan combined with Extended Release Nifedipine or Hydrochlorothiazide in the treatment of the Pure Systolic Hypertension.METHODS 240 cases of pure systolic hypertension were randomly divided into two groups,group A received Irbesartan and Extended Release Nifedipine while group B received Irbesartan and Hydrochlorothiazide.Principle of pharmacoeconomics was adopted to analyze cost-effectiveness of two treatment schemes.RESULTS The total effective rates of the two groups were 95% and 90% respectively,the cost effectiveness ratio of the two groups 4.23 and 3.78 respectively.No significant differences were found in the total effective rates between the two groups,but the cost effectiveness ratio of the group B was more less than the group A.CONCLUSION Taking everything into consideration,Irbesartan combined with Hydrochlorothiazide was the best scheme in the treatment of the pure systolic hypertension.