综合治疗膀胱混合癌的临床观察 |
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引用本文: | 章益峰,曹建伟,褚健,储传敏,张炯,陈元贵,黄钢,庄剑秋,郎根强.综合治疗膀胱混合癌的临床观察[J].国际泌尿系统杂志,2014,34(5):629-631. |
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作者姓名: | 章益峰 曹建伟 褚健 储传敏 张炯 陈元贵 黄钢 庄剑秋 郎根强 |
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作者单位: | 中国人民解放军411医院泌尿外科,上海,200081 |
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摘 要: | 目的 分析膀胱混合癌配合体部伽玛刀等综合治疗的疗效.方法 报告2003年7月至2013年8月本院收治的17例膀胱混合癌患者的临床资料,结合文献对该病的临床表现、诊断、治疗和加全身伽玛刀综合治疗以及预后情况进行讨论.结果 膀胱混合癌占同期362例膀胱恶性肿瘤的4.4%,移行、腺细胞混合癌5例,移行、鳞状细胞混合癌8例,移行、鳞状、腺细胞混合癌2例,鳞状、腺细胞混合癌2例.以膀胱刺激征和肉眼血尿为主要临床表现,治疗以膀胱全切和部分切除为主,术后辅助化疗或放疗,其1、3和5年的生存率分别为90.6%、52.8%和35.3%.结论 膀胱混合癌的恶性程度高,早期诊断和治疗是提高生存率的关键.全身伽玛刀配合手术及化疗等综合治疗有助于改善预后,提高生存率.
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关 键 词: | 膀胱肿瘤 |
Clinical study of multimodality appoaches for the bladder mixed tumor |
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Institution: | Zhang Yifeng,Cao Jianwei,Chu Jian( 1.Department of Urology,Military 411 Hospital,Shanghai 200081 ,China;) |
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Abstract: | Objectives To study the clinical effect of whole body γ-knife and multimodality appoaches on the bladder mixed tumor.Methods 17 case treated from jun 2003 to Aug 2013 were reviewed.The clinical manifestations,diagnosis,treatment,whole body γ-knife and multimodality appoaches and prognosis were discussed.Results 17 case of the bladder mixed tumor accounted for 4.4% of 362 bladder tumor patients in the same period,of which 5 of 17 were transitional squamous cell carcinoma,8 transitional adenocarcinoma,2 transitional squamous adenocarcinoma and 2 squamous adenocarcinoma a mixed tumor.Most of the patients had irritable bladder symptoms and hematurine.The main treatment was partial or total cystectomy.The over survival rates at 1,3 and 5a years post operation were 90.6%,52.8% and 35.3% respectively.Conclusions There wer higher malignancy and worse prognosis in bladder mixed tumor.Early diagnosis and therapy might prolong survival.Radical total cystectomy,whole body γ-knife and muhimodality appoaches on the bladder mixed tumor seems to be the best method of treatment. |
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Keywords: | Urinary Bladder Neoplasms |
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