Interaction of cholecystokinin with vasoactive intestinal peptide in body shaking response to ice-water immersion in rats |
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| Authors: | Goro Katsuura Kenji Yoshikawa Shinji Itoh |
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| Institution: | Shionogi Research Laboratories, Fukushima-ku, Osaka 553, Japan |
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| Abstract: | Interaction of cholecystokinin (CCK) with vasoactive intestinal peptide (VIP) in body shaking response to ice-water immersion was observed in pentobarbital-anesthetized rats. Although CCK itself had no influence on the response, VIP suppressed it and this effect of VIP was antagonized by simultaneous administration of sulfated octapeptide of CCK, but not by non-sulfated CCK. |
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| Keywords: | body shaking behavior cholecystokinin vasoactive intestinal peptide rat |
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