Meningitis with Burkitt like B-cell lymphoma in HIV infection |
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Authors: | R Bomfim da Paz H W Kölmel |
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Institution: | (1) Department of Neurology, Charité, Humboldt University, Schumannstr. 20/21, D-1000 Berlin, Germany;(2) Present address: Department of Neurology, Charité, Humboldt University, Schumannstr. 20/21, D-1000 Berlin, Germany |
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Abstract: | Malignant lymphoma with meningeal involvement was detected in 7 patients with stage IV HIV infection. The diagnosis of lymphoma was made at a maximum of four months before discovery of meningeal involvement. In our seven cases the lymphoma was B-cell type, one case expressed Kappa chains, four cases demonstrated Lambda chains and in two cases differentiation was not possible. A review of findings in all HIV positive patients treated in the same period revealed 10 non-Hodgkin lymphomas of the B-cell type, though meningeal and cerebral involvement was observed only in B-cell lymphoma of the Burkitt type. |
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Keywords: | AIDS B-cell lymphoma lymphomatous meningitis |
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