羟苯磺酸钙联合甲钴胺治疗糖尿病周围神经病变的疗效观察

目的 评价羟苯磺酸钙联合甲钴胺治疗糖尿病周围神经病变(DPN)的疗效.方法将60例DPN患者随机分为羟苯磺酸钙联合甲钴胺治疗组(n=30)和甲钴胺对照组(n=30),联合治疗组口服羟苯磺酸钙胶囊0.5 g、甲钴胺片0.5 mg；对照组口服甲钴胺片0.5 mg；均每日3次,疗程12周.观察治疗前后患者的腓神经传导速度、神...

Effective observation of calcium dobesilate combined with mecobalamin treatment on diabetic peripheral neuropathy

Objective To investigate the curative effects of calcium dobesilate combined with mecobalamin treatment on diabetic peripheral neuropathy (DPN). Methods Sixty patients with DPN were randomly divided into two groups. The treatment group (30 cases) were given calcium dobesilate 0.5 g and mecobalamin 0.5 mg, the control group (30 cases) were only given mecobalamin 0.5 mg, for 3 times one day and 12 weeks a course, respectively. The conductive velocity of nervusperoneus, neurological symptoms, and physical signs were assayed before and after treatment. Results The total effective rate was 93.3% in the treatment group and 63.3% in the control group, conductive velocity of nervusperoneus increased obviously in the treatment group, the neurological symptoms and physical signs improved more apparently in the treatment group than those in the control group. Conclusion The combination of calcium dobesilate and mecobalamin can obviously improve DPN.