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雪莲化学成分和药理活性研究进展
引用本文:李宁,波拉提·马卡比力,王歆君,肖皖,贾晓光,赵余庆. 雪莲化学成分和药理活性研究进展[J]. 现代药物与临床, 2011, 26(5): 344-348
作者姓名:李宁  波拉提·马卡比力  王歆君  肖皖  贾晓光  赵余庆
作者单位:沈阳药科大学中药学院基于靶点的药物设计与研究教育部重点实验室;新疆维吾尔自治区中药民族药研究所
基金项目:新疆自治区经贸委技术创新项目(2007001)
摘    要:雪莲是我国珍稀名贵的中药材,有着久远的药用历史以及丰富的民间用药基础.雪莲中含有的黄酮及其苷、倍半萜内酯、香豆素、木脂素、有机酸、氨基酸、甾体、多糖等成分,具有抗风湿、镇痛、调节心血管系统、抗癌、延缓衰老、计划生育、防辐射等生物活性,有很大的开发利用价值,应用前景良好.对药用雪莲近十年国内外的化学和药理活性研究进展进行...

关 键 词:雪莲  黄酮  倍半萜内酯  抗风湿  镇痛  抗痛

Advances in studies on chemical components and pharmacological activites of Saussureae Involucratae Herba
XIAO Wan,LI Ning,BOLATI Makabili,WANG Xin-jun;JIA Xiao-guang and ZHAO Yu-qing. Advances in studies on chemical components and pharmacological activites of Saussureae Involucratae Herba[J]. Drugs & Clinic, 2011, 26(5): 344-348
Authors:XIAO Wan,LI Ning,BOLATI Makabili,WANG Xin-jun  JIA Xiao-guang  ZHAO Yu-qing
Affiliation:1.Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education,School of Traditional Materia Medica,Shenyang Pharmaceutical University,Shenyang 110016,China 2.Xinjiang Institute of Chinese Materia Medica and Ethnodrug,Urumqi 830002,China
Abstract:Saussureae Involucratae Herba, a rare Chinese medicinal herb grown in Xinjiang Uygur Autonomous Region of China, has a long history and the basis of folk medicine usage. The plants mainly contain chemical constituents belonging to flavonoids, sesquiterpene lactones, coumarins, lignans, organic acids, amino acids, steroids, and polysaccharides. Their chemical constituents possess the important biological activities, such as anti-rheumatic, analgesic, regulating the cardiovascular system, anticancer, postponing senility, family planning, anti-radiation. The research development around the chemical constituents and biological activities in the latest ten years is reviewed and the clinical basis and development of Saussureae Involucratae Herba are explored in this paper.
Keywords:Saussureae Involucratae Herba   flavonoids   susquiterpene lactione   anti-rheumatic   analgesia   anticancer
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