合理选择穿刺针数和位点提高初次及重复前列腺活组织检查的阳性率:1293例临床分析

目的分析如何通过增加穿刺位点提高前列腺初次穿刺和重复穿刺的阳性率。方法 2006年1月—2009年6月共完成直肠超声引导经会阴前列腺穿刺1 293例,其中采用常规6点法穿刺250例,采用6+X法穿刺1 043例。比较不同穿刺方法的阳性率及其与前列腺特异性抗原(PSA)和经直肠超声(TRUS)检查表现的关系,并分析行重复活组织检查病例的阳性率。结果 6+X法穿刺的阳性率为46.4%,显著高于常规6点法的42.9%(P<0.05)。PSA≤4 ng/mL、>4且≤10 ng/mL、>10且≤20 ng/mL、>20且≤30 ng/mL4组中6+X法穿刺的阳性率均显著高于常规6点法(P值均<0.05);而PSA>30 ng/mL各组中,两种穿刺方法阳性率的差异无统计学意义(P值均>0.05)。超声表现正常、低回声结节、高回声或等回声结节3组的阳性率分别为23.1%、60.3%和32.1%,低回声结节组的阳性率显著高于另两组(P值均<0.05)。重复穿刺共54例,按最终病理检查结果分为良性和恶性组,恶性组首次穿刺发现高级别前列腺上皮内瘤样增生(PIN)、前列腺小腺泡不典型增生(ASAP)以及TRUS发现新的低回声结节...

Proper biopsy cores and sites to improve positive detecting rates of initial and repeated prostate biopsy: a clinical analysis of 1293 cases

Objective To analyze how to improve the positive detecting rates(PDR) of initial or repeated prostate biopsy by increasing the biopsy cores and sites.Methods A total of 1 293 patients received TRUS-guided transperineal prostate biopsy from Jan 2006 to June 2009,including 250 cases undergoing conventional sextant biopsy and 1 043 cases undergoing extended sextant biopsy.The PDR values were compared between the two groups and their relationship with prostate specific antigen(PSA) and transrectal ultrasound(TR...