牙菌斑产酸能力与龋易感性的关系

目的了解牙菌斑产酸量与龋齿易感性的关系。方法用高效毛细管电泳法分析患者牙菌斑中几种短链有机酸的含量，比较高活动龋者和无龋者体内和体外两种情况下菌斑产酸量的差异。结果无龋者和高龋者各２１人，分别进行体内和体外蔗糖反应实验，分析有机酸的产量。体内实验，高龋组乳酸的产量略高于无龋组，但统计学无显著意义；而体外实验，两组无差异。结论决定龋或非龋的主要因素可能不是菌斑糖代谢后生成有机酸量的多少，而是酸在局部的滞留状态

Study of acidogenesis of dental plaque on cariogenesis using capillary electrophoresis

OBJECTIVE: The aim was to investigate the relationship of acid production with caries onset. METHODS: Short-chain organic acids of dental plaque from individual subjects were analyzed by capillary electrophoresis. Dental plaques from subjects of caries free and caries active, 21 for each group, were analyzed for 7 short-chain organic acids. RESULTS: The in vivo production of lactic acid was a bit higher in caries active-group than in caries free group (but no statistic significance), however, no difference in vitro. CONCLUSION: Therefore, it is hard to relate the net quantity of acid production to the caries onset.