Abstract: | The adherence of Pseudomonas aeruginosa strains to human epithelial cells from the buccal mucosa, large intestine and urinary tract was studied. Strains resistant to gentamicin and carbenicillin, derived by laboratory training, exhibited enhanced adherence as compared to their sensitive parent strain. The same was found with a strain showing an R-factor acquired resistance to gentamicin. This phenomenon was observed with all epithelial cells tested regardless of their anatomical origin. These results suggest that resistant strains of P. aeruginosa are more likely to colonise mucosal surfaces. |