Acquired growth hormone deficiency due to pituitary stalk transection after head trauma in childhood |
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Authors: | C. Yamanaka T. Momoi I. Fujisawa K. Kikuchi M. Kaji H. Sasaki T. Yorifuji H. Mikawa |
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Affiliation: | (1) Department of Pediatrics, Kyoto University Faculty of Medicine, Shogoin Kawahara-cho Sakvo-ku, 606 Kvoto, Japan;(2) Department of Radiology and Nuclear Medicine, Kyoto University Faculty of Medicine, Shogoin Kawahara-cho, Sakvo-ku, 606, Kyoto, Japan;(3) Department of Pediatrics, Wakayama Red Cross Hospital, Wakayma, Japan;(4) Department of Radiology, Kishiwada City Hospital, Kishiwada, Japan;(5) Department of Pediatrics, Shimane Medical University, Izumo, Japan |
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Abstract: | Two patients are reported with growth hormone deficiency due to head trauma in childhood. Although their injuries were outwardly only slight and there was no loss of consciousness and no subsequent neurological deficits, they exhibited gradual growth retardation from the time of the trauma. Provocative endocrinological tests showed growth hormone deficiency and MRI showed transection of the pituitary stalk. These findings suggest that ordinary head trauma, as well as perinatal insult and congenital abnormalities, could be a cause of growth hormone deficiency. |
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Keywords: | Magnetic resonance imaging Growth hormone deficiency Head trauma |
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