颈总动脉内膜中膜厚度与脑梗死复发的关系

目的:探讨颈总动脉内膜中膜厚度(CCA-IMT)与脑梗死复发的关系。方法:连续收集急性脑梗死住院患者265例,通过颈动脉彩超检查CCA-IMT,随访观察有无脑梗死复发。结果:随访12个月内,265例脑梗死患者中有25例(9.4%)复发脑梗死,复发与无复发脑梗死患者间总胆固醇、低密度脂蛋白胆固醇、空腹血糖和CCA-IMT水平差异有显著性(P<0.05)。把两组间存在显著差异的指标引入Logistic回归方程,结果显示CCA-IMT是脑梗死复发的独立危险因素。结论:CCA-IMT是脑梗死复发的独立危险因素。

the Relationship between common carotid artery intima-media thickness and Cerebral Infarction Recurrence

Objective The goal of the present study was to investigate the relationship between common carotid artery intima-media thickness (CCA-IMT) and cerebral infarction(CI) recurrence. Methods We consecutively recruited 265 patients with acute CI, ultrasonography was performed to evaluate the CCA-IMT. All patients were followed-up prospectively and the outcome event of interest was recurrent CI. Results Among 265 patients with CI, 25 patients (9.43％) recurrent CI were documented in the 12 months that followed. The level of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), fasting blood glucose (FBG) and CCA-IMT between patients who experienced recurrent CI and those free of recurrent CI was significant difference(P＜0.05). Logistic regression analysis show that CCA-IMT is the independent risk factor of CI recurrence. Conclusion Increased common carotid artery intima-media thickness has a higher risk of long-term stroke recurrence.