中国人镧系元素膳食摄入量和主要器官及组织负荷量研究

目的 测定我国成年男子膳食食品和主要器官、组织中镧系元素浓度和估算其膳食日摄入量和器官、组织负荷量。方法 在我国不同膳食类型4地区采集21例急死正常尸体10种主要器官、组织样品，连同过去所采当地食品和31例尸体6种器官、组织样品，采用ICP—MS或INAA法及必要的质量控制措施，分别测定了11和14种镧系元素浓度。按当地膳食组成和中同参考人器官组织重量估算了摄入量和器官、组织负荷量。结果 获得了我国12类食品和10种主要器官、组织样品中14种镧系元素浓度、摄入量和相应器官、组织负荷量。结论 本研究首次获得我国各类食品和成年男子10种器官组织中11种镧系元素浓度、相应膳食口摄入量和负荷量。所获结果为确定中国参考人镧系元素相应参数提供较前更为系统的依据，也为不同镧系元素、食品和器官组织提供了比较和背景值的国情资料。

Dietary intake and burden of lanthanide in main organs and tissues for Chinese man

Objective To determine lanthanide concentrations in dietary foods and main organs or tissues for Chinese adult man and to estimate their daily intakes by ingestion and organ or tissue burdens. Methods Ten kinds of organ or tissue samples collected in autopsy from 21 supplemental subjects of 4 areas with different dietary types in China who died suddenly,and had been healthy and normal before death.The concentrations of 11 lanthanide in foods and 14 lanthanide in these organ or tissue samples,including those collected from 31 subjects in the past,were analyzed by using ICP-MS or INAA technique as well as necessary QC measures.With uses of the local diet composition and relevant organ or tissue weights for Chinese Reference Man,their daily intakes and organ or tissue burdens were estimated. Results The concentrations of 14 lanthanide in 12 categories of foods and 10 kinds of organ or tissue samples,their dietary daily intakes and organ or tissue burdens for Chinese adult men were obtained. Conclusion Besides updating the relevant data of La,Ce and Eu in 5 kinds of organ or tissue and diet,this research obtained data on concentrations of other 11 lanthanide in Chinese foods and 10 kinds of organ or tissue,their daily intakes and burdens for the first time in China.The results provide more systematic bases for developing the parameters of Chinese Reference Man than before.This study provides also comparative data for different kinds of lanthanide,foods,organs or tissues and also the background values of Chinese soil.