脑苷肌肽对急性颅脑损伤疗效的临床观察

目的观察脑苷肌肽对急性颅脑损伤患者的疗效。方法将102例急性脑外伤患者随机分为静滴脑苷肌肽组(治疗组52例)和单纯药物治疗组(对比组50例),观察患者GCS评分的变化和3个月后GOS的比较。结果GCS的变化,治疗组13~15分组、9~12分组和3~8分组治疗前后比较,差异具有显著性P<0.05。3个月后GOS的比较,治疗组恢复良好和中残的病例是总数的89.4%,对照组为64.6%,两者比较差异具有显著性P<0.05。结论脑苷肌肽应用于急性颅脑损伤患者时能减轻脑水肿,促进脑功能恢复,降低死亡率,改善预后。

Observation of Acute Brain Injury Treatment with Cattle Encephalon Glycoside and Ignotin Injection

Objective:To investigate the curative effect of Cattle Encephalon Glycoside and Ignotin Injection in acute brain injury treatment.Methods:102 patients with acute brain injury were included in the randomized and controlled study,52 cases in studied group were treated with Cattle Encephalon Glycoside Ignotin Injection,50 cases in controlled group were treated with traditional medication. Glasgow Coma Scale (GCS) and Glasgow Outcome Scale(GOS) of the patients were evaluated after 3 months.Results: After 3 months,GCS were significantly higher than those treatment in the subgroups of the treated group (P<0.05) 89.4% patients with good recovery or moderate handicap in the treated group,there was significant difference of GOS between them (P<0.05). Conclusion: Cattle Encephalon Glycoside and Ignotin Injection has been shown to mitigate brain edema,reestablish functions of injured brain,reduce the patients' mortality and improve their life-quality and prognosis.