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实验性犬急性心肌梗塞早期MRI诊断研究
引用本文:杨淑琴,于文玲,赵永生. 实验性犬急性心肌梗塞早期MRI诊断研究[J]. 吉林大学学报(医学版), 2001, 27(6): 670-672
作者姓名:杨淑琴  于文玲  赵永生
作者单位:吉林大学中日联谊医院放射线科,吉林,长春,130031
摘    要:目的 :探讨 MRI对急性心肌梗塞早期的诊断价值。方法 :采用闭胸式方法复制犬急性心肌梗塞模型 5只 ,于术前行 MRI平扫 ,术后 1h行 MRI平扫及 Gd- DTPA增强扫描 ,观察不同时间磁共振信号强度改变。结果 :栓塞后 1h平扫 T1WI示正常心肌与梗塞区之间信号强度差异无显著性 ;T2 WI示栓塞区信号强度明显增高 ,增强后示栓塞区明显强化。结论 :MRI对急性心肌梗塞早期诊断具有重要价值。

关 键 词:急性心肌梗塞  磁共振成像  动物实验
文章编号:0253-3707(2001)06-0670-03
修稿时间:2000-12-28

MRI study on diagnosis of experimental canine early-phase acute myocardial infarction
YANG Shu qin,YU Wen ling,ZHAO Yong sheng. MRI study on diagnosis of experimental canine early-phase acute myocardial infarction[J]. Journal of Jilin University: Med Ed, 2001, 27(6): 670-672
Authors:YANG Shu qin  YU Wen ling  ZHAO Yong sheng
Abstract:Objective:To explore the diagnostic value of MRI for early phase acute myocardial infarction.Methods:Five canine models of acute myocardial infarction were made by closed chest methods.Pre contrast MRI was performed before occlusion and both pre and post contrast MRI was performed one hour after occlusion.The changes of MRI signal intensity were observed at different time points.Results:One hour after occlusion,the signal intensity of the infarcted region increased obviously on T 2W pro contrast.After administration of Gd DTPA,the focus reveals a notable enhancement.Conclusion:MRI is of great value in diagnosing early phase acute myocardial infarction.
Keywords:acute myocardial infarction  magnetic resonansce imaging (MRI)  animal  laboratory
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