多指标综合评价法在高血压病中医证候分类研究中的应用

目的?获得高血压病相对科学、客观的证候及证候要素，并对证候要素所对应的指标进行重要性评价。方法?以肝火亢盛证为例来说明多指标综合评价法在高血压病证候分类研究中的应用。采用多指标综合评价法，评价高血压病在传统流行病学调查以及专家咨询中所获得的证候及证候要素所对应的各指标的重要性。结果?高血压病肝火亢盛证包含18个指标，经综合评价后部分指标的重要性发生了改变，如舌红、黄苔、急躁易怒、口苦目眩、半身麻木等。该证候包含2证候要素，其分别对应的指标经综合评价后，大部分的重要性与之前的研究结果一致，少数指标的重要性发生轻微改变，如舌红、弦脉等。结论?多指标综合评价法可以将临床流行病学调查的统计分析结果以及专家经验有机地结合起来，既避免了纯统计分析脱离临床的弊端，又解决了专家经验过于主观的问题。 

Application of Multi-index Comprehensive Evaluation Method to TCM Syndrome Classification of Hypertension

OBJECTIVE?To obtain the scientific and objective syndrome and syndrome factors for hypertension and to evaluate the importance of corresponding indexes of each syndrome factors. METHODS?Overabundant liver-fire syndrome was cited as the example to illustrate the syndrome factors of hypertension and the analysis and evaluation of its indexes. Multi-index comprehensive evaluation method was applied to evaluate the hypertension syndromes obtained under the structural equation model and through expert consultation， with importance of each indexes being analyzed. RESULTS?18 indexes were included in the hypertension of overabundant liver-fire syndrome. Among which， the importance of partial indexes like red tongue， yellow tongue coating， prone to lose temper， bitter sensation in the mouth， dizziness， hemianesthesia experienced changes based on comprehensive evaluation. Two syndrome factors were included in this syndrome. It was proved that the majority of index importance through comprehensive evaluation was almost the same as the previous study results， except for some small index changes like red tongue and wary pulse. CONCLUSION?Multi-index comprehensive evaluation method can be used to analyze the statistical results of both clinical epidemiological investigation and expert experience， which not only avoids the disadvantages of pure statistical estimation， but also solves the problem of subjective bias induced by expert experience.