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药用植物到手香水提液镇咳祛痰作用研究
引用本文:王玲,管淑玉,梁颖. 药用植物到手香水提液镇咳祛痰作用研究[J]. 安徽医药, 2018, 22(3): 419-421. DOI: 10.3969/j.issn.1009-6469.2018.03.008
作者姓名:王玲  管淑玉  梁颖
作者单位:广东食品药品职业学院,广东广州,510520;广东药科大学,广东广州,510006
基金项目:广东省中医药局建设中医药强省科研项目(20141200)药用植物到手香水提液镇咳祛痰作用研究王玲1,管淑玉2,梁颖1 (1.广东食品药品职业学院,广东 广州 510520;2.广东药科大学,广东 广州 510006)药用植物到手香水提液镇咳祛痰作用研究王玲1,管淑玉2,梁颖1 Antitussive and expectorant effects of water soluble extractive of Coleus amboinicus LourWANG Ling1,GUAN Shuyu2,LIANG Ying1
摘    要:目的 对到手香水提液镇咳祛痰作用研究.方法 采用水蒸气蒸馏法对到手香水提液进行提取,采用到手香水提液对小鼠进行氨水引咳法的镇咳实验,采用到手香水提液对小鼠进行气管酚红排泄量影响的祛痰实验.结果 到手香水提液6、12、24 g·kg-1剂量组对小鼠的镇咳、祛痰作用与对照组比较,差异有统计学意义.结论 到手香水提液有显著的镇咳祛痰作用,具有医药开发利用价值.

关 键 词:到手香  水提液  镇咳  祛痰
收稿时间:2017-04-28
修稿时间:2017-08-30

Antitussive and expectorant effects of water soluble extractive of Coleus amboinicus Lour
WANG Ling,GUAN Shuyu and LIANG Ying. Antitussive and expectorant effects of water soluble extractive of Coleus amboinicus Lour[J]. Anhui Medical and Pharmaceutical Journal, 2018, 22(3): 419-421. DOI: 10.3969/j.issn.1009-6469.2018.03.008
Authors:WANG Ling  GUAN Shuyu  LIANG Ying
Affiliation:Guangdong Food and Drug Vocational College,Guangzhou,Guangdong 510520,China,Guangdong Pharmaceutical University,Guangzhou,Guangdong 510006,China and Guangdong Food and Drug Vocational College,Guangzhou,Guangdong 510520,China
Abstract:Objective To investigate the antitussive and expectorant effects of water soluble extractive of Coleus amboinicus Lour.Methods The antitussive effects were investigated through observing the cough time and 50% effect time induced by ammonium hydroxide in mice.The expectorant activity was studied by testing the amount of phlegm secreted in mice.Results Water soluble extractive (6,12,24 g · kg-1) of Coleus amboinicus Lour.could obviously prolong the latent period,decrease the frequency of cough and promote mouse tracheal phenol red secretion in comparison with the control group.Conclusions Water soluble extractive of Coleus amboinicus Lour.has significant antitussive and expectorant efficacy.
Keywords:Coleus amboinicus Lour  water soluble extractive  antitussive  expectorant
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