| 双氯芬酸钠缓释胶囊的制备及其释药特性研究 |
| |
| 引用本文： | 林宁,肖学成,饶泽萍,王蓉,丁广林.双氯芬酸钠缓释胶囊的制备及其释药特性研究[J].华西药学杂志,2002,17(2):118-119. |
| |
| 作者姓名： | 林宁 肖学成 饶泽萍 王蓉 丁广林 |
| |
| 作者单位： | 湖北药检高等专科学校,湖北,武汉,430064 |
| |
| 摘 要： | 目的：制备双氯芬酸钠缓释胶囊（DS－SRC），并对其体外释药特性进行研究。方法：采用紫外分光光度法测定DS－SRC的释放度，并进行释放机制的研究。结果：DS－SRC体外释放曲线符合Higuchi方程；该制剂比普通片剂释药稳定、持续作用时间长。结论：体外试验表明DC－SRC具有明显的缓释作用。
|
| 关 键 词： | 双氯芬酸钠 缓释胶囊 制备 释药特性 研究 |
| 文章编号： | 1006-0103(2002)02-0118-02 |
| 修稿时间： | 2001年11月1日 |
STUDY ON THE PREPARATION AND RELEASE PROPERTIES OF DICLOFENAC SODIUM SUSTAINED RELEASE CAPSULES |
| |
| LIN Ning,XIAO Xue-cheng,RAO Ze-ping,WANG Rong,DING Guang-lin Hubei College of Pharmacy and Clinical Inspection Technology,Wuhan ,China.STUDY ON THE PREPARATION AND RELEASE PROPERTIES OF DICLOFENAC SODIUM SUSTAINED RELEASE CAPSULES[J].West China Journal of Pharmaceutical Sciences,2002,17(2):118-119. |
| |
| Authors: | LIN Ning XIAO Xue-cheng RAO Ze-ping WANG Rong DING Guang-lin Hubei College of Pharmacy and Clinical Inspection Technology Wuhan China |
| |
| Institution: | LIN Ning,XIAO Xue-cheng,RAO Ze-ping,WANG Rong,DING Guang-lin Hubei College of Pharmacy and Clinical Inspection Technology,Wuhan 430064,China |
| |
| Abstract: | OBJECTIVE To prepare a diclofenac sodium sustained release capsules(DS-SRC) and study its release properties in vitro.METHODS To determine release rate in vitro of DS-SRC by UV and study its release mechanism.RESULTS The release profile of DS-SRC corresponded with Higuchi kinetics. The kind of sustained release preparation has some features compared with common tablets, such as release stability and last long times. CONCLUSIONS DS-SRC showed a obviously sustained release effect. |
| |
| Keywords: | Diclofence sodium Sustained release capsules Release rates |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
