| 温阳活血中药复方对冠心病(心)阳虚血瘀证大鼠vWF浓度的影响 |
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| 引用本文： | 张明雪,曹洪欣,常艳鹏,刘宁. 温阳活血中药复方对冠心病(心)阳虚血瘀证大鼠vWF浓度的影响[J]. 世界科学技术-中医药现代化, 2008, 10(4): 48-52 |
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| 作者姓名： | 张明雪 曹洪欣 常艳鹏 刘宁 |
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| 作者单位： | 辽宁中医药大学附属医院,沈阳,110032;中国中医科学院,北京,100700 |
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| 基金项目： | 国家自然科学基金重大研究项目(90709002):冠心病证候要素、证候特征、证候病机演变规律及病证结合研究，负责人：张明雪; 国家中医药管理局项目(04-05JP13):温阳活血中药复方调控冠心病血小板内受体、信号转导的作用机理研究，负责人：张明寻; 辽宁省教育厅(20040218):益气活血中药复方防治动脉粥样硬化炎症机理研究，负责人：张明雪。 |
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| 摘 要： | 目的:研究温阳活血中药复方对冠心痛(心)阳虚血瘀证大鼠vWF浓度的影响.方法:建立冠心病(心)阳虚血瘀证大鼠模型,观察温阳活血中药复方对冠心病(心)阳虚血瘀证大鼠vWF浓度的影响.结果:温阳活血中药复方治疗组与模型组比较,能够显著降低vWF的浓度.结论:温阳活血中药复方能够降低vWF的浓度,抑制释放反应和花生四烯酸代谢(AA代谢),保护内皮细胞,抑制血小板活化.
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| 关 键 词： | 冠心病阳虚血瘀证 温阳活血中药复方 vWF |
| 收稿时间： | 2008-04-30 |
| 修稿时间： | 2008-05-11 |
Effect of TCM Wenyang Huoxue Compound Recipe on vWF Concentration of a Heart Yang Deficiency and Blood Stasis Rat Model |
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| Zhang Mingxue,Coo Hongxin,Chang Yanpeng and Liu Ming. Effect of TCM Wenyang Huoxue Compound Recipe on vWF Concentration of a Heart Yang Deficiency and Blood Stasis Rat Model[J]. World Science and Technology—Modernization of Traditional Chinese Medicine and Materia Medica, 2008, 10(4): 48-52 |
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| Authors: | Zhang Mingxue Coo Hongxin Chang Yanpeng Liu Ming |
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| Affiliation: | Liaoning TCM University Hospital; Shenyang 110032;China Academy of Chinese Medical Sciences Beijing 100700;Liaoning TCM University Hospital; Shenyang 110032;Liaoning TCM University Hospital; Shenyang 110032 |
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| Abstract: | Authors studied the effects of a TCM compound recipe named Wenyang Huoxue(wanning yang and promoting blood circulation)on vWF concentration of a rat model featured with heart Yang deficiency and blood stasis of coro- nary heart disease.In the study,rats were induced to have CHD due to heart Yang deficiency and bloodstasis.Mean- while,the effects of the complex recipe on vWF concentration of the rat model were observed.Comparing with the model group,the compound recipe showed a significant difference.The rec... |
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| Keywords: | coronary heart disease with heart Yang deficiency warming yang and promoting blood circulation TCM compound recipe vWF |
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