中药中残留农药在制药工艺中的归属与去除

目的:探讨3种提取工艺情况下人参中有机氯农药的归属。方法:采用水煎煮工艺及95%乙醇、50%乙醇加热回流工艺对人参有效成分进行提取后,用毛细管气相色谱法测定煎煮(提取)液中的有机氯农药含量。结果:以95%醇提溶出率最高,50%醇提溶出率次之,水煎过程溶出率最少。结论:醇提对中药材中有机氯农药有较高的溶出率,而水煎煮过程对中药材中有机氯农药的溶出率很低,残留农药大部分随药渣去除。因此情况允许的条件下应尽量采用水煎工艺提取药材中的有效成分,必须采用醇提工艺时应考虑去除提取过程伴随溶出的残留农药,以避免残留农药可能的安全风险。

Determining the Organochlorinated Pesticides Dissolve Ratio Using Different Extract Methods

Authors studied three different ginsing OCPs extraction methods and associated effects.The three methods work with decoction and extraction at 95%-ethanol and 50%-ethanol respectively.The amount of OCPs extracted was mea- sured by gas chromatography,and the extraction results were compared among the three methods.95%-ethanol pro- duced the highest extraction,followed by 50%-ethanol.The decoction sat at the lowest when the amount of OCPs was used as a standard.It is concluded that ethanol produces a much ric...