| 糖尿病治疗中多肽类药物新型缓控释给药制剂的研究进展 |
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| 引用本文： | 宣吉明,程玉松,高静,钟延强. 糖尿病治疗中多肽类药物新型缓控释给药制剂的研究进展[J]. 药学实践杂志, 2012, 30(1): 14-18,37 |
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| 作者姓名： | 宣吉明 程玉松 高静 钟延强 |
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| 作者单位： | 1. 第二军医大学药学院药剂教研室,上海,200433
2. 南京军区联勤部卫生部上海药品器材供应站,上海,200052 |
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| 摘 要： | 多肽类降血糖药物具有模拟正常人的生理性胰岛素分泌的功能,并且其降糖作用与患者血糖水平有关,很少发生低血糖事件。现就治疗糖尿病的多肽类药物新型缓控释制剂作一综述。
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| 关 键 词： | 糖尿病治疗 多肽 缓控释给药 |
| 收稿时间： | 2011-05-22 |
| 修稿时间： | 2011-12-15 |
Developments of sustained and controlled release delivery systems of peptides in treatment of diabetes |
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| XUAN Ji-ming,CHENG Yu-song,GAO Jing and ZHONG Yan-qiang. Developments of sustained and controlled release delivery systems of peptides in treatment of diabetes[J]. The Journal of Pharmaceutical Practice, 2012, 30(1): 14-18,37 |
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| Authors: | XUAN Ji-ming CHENG Yu-song GAO Jing ZHONG Yan-qiang |
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| Affiliation: | Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Drugs and Instruments Supplying station in Nanjing,Department of health of Jiont logistics of Nanjing Military Region,Shanghai 200052,China;Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;Department of Pharmaceutics, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Peptide analog of hypoglycemic drugs had a normal physiological function of insulin secretion. The hypoglycemic effect of peptide depended on blood glucose levels of patients, which induced very few incidents of hypoglycemia. Peptides of sustained and controlled release delivery systems in diabetes treatment were summed up in this paper. |
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| Keywords: | diabetes treatment peptide sustained and controlled release delivery systems |
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