黑地黄丸对慢性肾衰竭患者肾功能指标影响 |
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引用本文: | 周长磊,王芳,董彬,吴俊燕,纪俊俊,张法荣[指导]. 黑地黄丸对慢性肾衰竭患者肾功能指标影响[J]. 辽宁中医学院学报, 2013, 0(11): 135-136 |
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作者姓名: | 周长磊 王芳 董彬 吴俊燕 纪俊俊 张法荣[指导] |
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作者单位: | [1]山东中医药大学,山东济南250013 [2]山东中医药大学附属医院,山东济南250013 |
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基金项目: | 山东省科技发展计划项目(2010G0020214) |
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摘 要: | 目的:观察黑地黄丸对慢性肾衰竭患者肾功能指标的影响。方法:入选160例病例,采用前瞻性、随机、阳性药物平行对照方法进行临床试验,试验结束后观察患者血肌酐(Scr)、血尿素氮(BUN)、内生肌酐清除率(Ccr)等指标变化。结果:试验组治疗后血Scr水平低于治疗前,有统计学意义(P〈0.05),试验组治疗后血Ccr水平高于治疗前,有高度统计学意义(P〈0.01);两组治疗后比较血Scr水平与Ccr水平比较,差异有统计学意义(P〈0.05);两组治疗后对血BUN、CO2-CP影响比较,差异无统计学意义(P〉0.05)。结论:黑地黄丸可降低患者Scr、Ccr,对BUN无影响。
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关 键 词: | 黑地黄丸 慢性肾衰竭 血肌酐 |
Influence of Heidihuang Pill on Renal Index of Patients with Chronic Renal Failure |
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Affiliation: | ZHOU Changlei , WANG Fang, DONG Bin, WU Junyan,JI Junjun, Advisor: ZHANG Farong ( 1.Shandong University of Traditional Chinese Medicine, Ji'nan 250013, Shandong, China; 2.Shandong University Hospital of Traditional Chinese Medicine, Ji'nan 250013, Shandong, China ) |
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Abstract: | Objective:To observe the influence of Heidihuang Pill on renal index of patients with chronic renal failure. Methods: 160 cases were selected, using the prospective, randomized clinical trials and positive drug parallel contrast method. After the experiment, patients' serum creatinine ( Ser ), bloodurea nitrogen ( BUN ), endogenous creatinine clearance rate ( Ccr ) indicators were observed. Results : The blood level of Scr in experimental group was lower than that before treatment, and there was statistically significant difference ( P〈0.05 ). The blood level of Ccr in the experimental group after treatment was higher than that before treatment, and there was highly statistically significant difference ( P〈0.01 ). Blood levels of Scr and Ccr comparison was statistically significant ( P〈0.05 ). After treatment, the two groups' effects on blood BUN and CO2-CP had no statistically significant difference ( P〉0.05 ). Conclusion : Heidihuang Pill can reduce patients' Scr and Ccr, without any influence on BUN. |
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Keywords: | Heidihuang Pill chronic renal failure serum creatinine |
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