| 黄芩清热燥湿和泻火解毒药效组分分析 |
| |
| 引用本文： | 刘晶晶,张贵君,彭慧,董文茜,高晓美. 黄芩清热燥湿和泻火解毒药效组分分析[J]. 辽宁中医学院学报, 2013, 0(11): 78-80 |
| |
| 作者姓名： | 刘晶晶 张贵君 彭慧 董文茜 高晓美 |
| |
| 作者单位： | 北京中医药大学中药学院,北京100102 |
| |
| 摘 要： | 目的：研究黄芩及其复方汤剂清热燥湿、泻火解毒的药效组分,探讨饮片配伍、剂型与药效组分的相关性,为新药的研发和质量评价体系的建立提供科学数据。方法：采用单味药、药对和复方及其制剂对应的方法制备样品并进行对照,采用反相高效液相色谱法RP-HPLC测定药效组分的含量。结果：黄芩的药效组分是黄芩苷-汉黄芩苷-黄芩素-汉黄芩素,其含量依次为（47.602±0.736）、（9.11±0.068）、（4.782±0.174）、（1.286±0.071）mg·g-1。结论：黄芩药效组分黄芩苷-汉黄芩苷-黄芩素-汉黄芩素,其清热燥湿组分是26.38∶4.96∶2.60∶1;其泻火解毒组分是28.83∶5.42∶1.89∶1。且各药效组分之间有显著性差异（P〈0.01）。药效组分与配伍和剂型相关,同一个单味药,由于配伍不同,其药效组分不同。
|
| 关 键 词： | 黄芩 配伍 药效组分 RP-HPLC 相关性 |
Analysis of Active Components Alignments in Scutellaria on Basis of Functions of Clearing Away Heat and Eliminating Dampness and Purging Fire and Removing Toxic Material |
| |
| LIU Jingjing,ZHANG Guijun,PENG Hui,DONG Wenxi,GAO Xiaomei. Analysis of Active Components Alignments in Scutellaria on Basis of Functions of Clearing Away Heat and Eliminating Dampness and Purging Fire and Removing Toxic Material[J]. Journal of Liaoning College of Traditional Chinese Medicine, 2013, 0(11): 78-80 |
| |
| Authors: | LIU Jingjing ZHANG Guijun PENG Hui DONG Wenxi GAO Xiaomei |
| |
| Affiliation: | ( School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China ) |
| |
| Abstract: | |
| |
| Keywords: | scutellaria compatibility of medicines active component alignment HPLC correlation |
| 本文献已被 维普 等数据库收录！ |
|
