Nucleotide sequence of streptococcal pyrogenic exotoxin type C. |
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| Authors: | S C Goshorn and P M Schlievert |
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| Affiliation: | Department of Microbiology, University of Minnesota Medical School, Minneapolis 55455. |
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| Abstract: | The nucleotide sequence of the gene speC, encoding streptococcal pyrogenic exotoxin type C (SPE C), was determined. The gene encoded a mature protein of 208 amino acids, with a calculated molecular weight of 24,354. The mature amino acid sequence of SPE C was analyzed for homology with the amino acid sequences of streptococcal pyrogenic exotoxin type A, the staphylococcal enterotoxins, and toxic shock syndrome toxin-1. Of these, SPE C shared the greatest amount of homology with streptococcal exotoxin type A. |
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