血常规指标对老年急诊骨盆及下肢骨折手术患者术后深静脉血栓形成的影响及预测价值分析

目的 分析血常规指标对老年急诊骨盆及下肢骨折手术患者术后深静脉血栓(DVT)形成的影响及预测价值。方法 回顾性分析2020年6月至2022年2月洛阳市东方人民医院收治的82例急诊行骨盆及下肢骨折手术治疗的老年患者的临床资料，收集患者性别、年龄等一般资料以及术前白细胞计数(WBC)、红细胞计数(RBC)等血常规资料，并根据术后是否出现DVT将其分为DVT组与非DVT组，分析血常规指标对老年急诊骨盆及下肢骨折手术患者术后DVT形成的影响及预测价值。结果 82例急诊行骨盆及下肢骨折手术治疗的老年患者中，19例(23.17%)患者术后出现DVT，设为DVT组；63例(76.83%)患者术后未出现DVT，设为非DVT组。多因素Logistic回归分析结果显示，RBC、中性粒细胞计数(NEU)为老年急诊骨盆及下肢骨折手术患者术后DVT形成的影响因素(95%CI为1.411～7.553、 1.450～5.476,P=0.006、 0.003)。受试者操作特征(ROC)曲线分析结果显示，当RBC、 NEU的截断值分别为4.05×10¹²/L、 6.40×10⁹

Analysis of the Influence and Predictive Value of Routine Blood Indicators on Deep Vein Thrombosis Formation in Elderly Patients after Emergency Pelvic and Lower Limb Fracture Surgery

【Abstract】 Objective To analyze the influence and predictive value of routine blood indicators on deep vein thrombosis (DVT) formation in elderly patients after emergency pelvic and lower limb fracture surgery. Methods The clinical data of 82 elderly patients who underwent emergency pelvic and lower limb fracture surgery in Luoyang Dongfang People’s Hospital from June 2020 to February 2022 were retrospectively analyzed to collect their general data and blood routine data including sex, age, preoperative white blood cell count (WBC) and red blood cell count (RBC), etc. Thepatients were divided into DVT group and non-DVT group according to the occurrence of DVT after surgery to analyze the influence and predictive value of routine blood indicators on DVT formation in elderly patients after emergency pelvic and lower limb fracture surgery. Results Among the 82 elderly patients who underwent emergency pelvic and lower limb fracture surgery, 19 cases (23.17%) developed DVT, being set as the DVT group, and the other 63 patients (76.83%) did not develop DVT, being set as the non-DVT group. The results of multifactorial Logistic regression analysis showed that RBC and neutrophil count (NEU) were the influential factors of DVT formation in elderly patients after emergency pelvic and lower limb fracture surgery (95%CI: 1.411-7.553, 1.450-5.476, P= 0.006 and 0.003). The receiver operating characteristic (ROC) curve analysis showed that, when the cutoff values of RBC and NEU were 4.05×1012/ L and 6.40×109/ Lrespectively, the area under the curve (AUC) for predicting DVT formation in elderly patients after emergency pelvic and lower extremity fracture surgery was 0.811 and 0.780 respectively, with the sensitivity being 63.2% and 52.6%, and the specificity being 95.2% and 88.9% respectively, while the AUC value of their combined detection was 0.842, with the sensitivity being 84.2%, and the specificity being 84.1%. Conclusion The DVT formation in elderly patients after emergency pelvic and lower limb fracture surgery is associated with RBC and NEU. RBC and NEU detection can help predict the occurrence of DVT.