| Abstract: | Experiments on male mice of A/He strain have shown that an increase in the level of gamma-aminobutyric acid (GABA) or emotional stress block an increase in the blood level of testosterone caused by the presence of a recipient female mouse. Under the conditions of sex activation the blockade of GABAA-receptors eliminates partially the inhibitory effect of emotional stress on androgen function of a single male or a micropopulation of animals. A conclusion is that the inhibitory effect of emotional stress on the blood level of testosterone during sex activation is achieved through the GABAergic mechanism by means of excitation, at least partially, of GABAA-receptors. The revealed mechanism can play an adaptive role in stress under natural conditions. |
