新生儿缺氧缺血性脑病172例临床分析

目的总结新生儿缺氧缺血性脑病(HIE)的临床表现及防治措施。方法回顾分析2000年1月至2005年10月收住院172例新生儿缺氧缺血性脑病的临床资料。结果依照诊断标准及临床分度为轻度48例,中度104例,重度20例。确诊后对患儿进行密切监护,纠正电解质紊乱,恢复脑血流灌注,控制脑水肿,抗惊厥,维持正常脑代谢等治疗。疗效:治愈112例,好转44例,放弃治疗8例,死亡8例。结论围产期脑损伤是新生儿缺氧缺血性脑病发生的主要原因。做好围产期保健,重视HIE的防治,对改善预后,减少后遗症,降低HIE的病死率具有重要的意义。

Clinical analysis of 172 neonatal hypoxicischemic encephalopathy cases

Objective:To summarize the clinical features and prevention and cure measures of neonatal hypoxicischemic eneephalopathy(HIE).Methods: Retrospective study of 172 HIE cases from January 2000 to October 2005 was made.Results: These cases were divided into three parts:48 cases of low grades,104 cases of the moderate,and 20 cases of the severe,acccrding to dignostic criteria and clinical classificaflon.After dignosis,careful monitoring,disorder of electrolyte rectifying,renew of cerebrovascular perfusion,control of brain edema,resisting of convculsion,and maintain ing normal brain metabolization were carried out and the curative results were that 112 neonates were healed,44 straightened,8 abandoned,and 8 died.Conclusion: Perinatal brain injury is the main cause of HIE.It also suggests that proper perinatal health care and improvement of prevention and cure of HIE are of great importance to improve prognosis,decrease sequelae,and reduce mortality of HIE.