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Reduced Patient-Reported Outcome Scores Associate With Level of Fibrosis in Patients With Nonalcoholic Steatohepatitis |
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| Authors: | Zobair M. Younossi Maria Stepanova Quentin M. Anstee Eric J. Lawitz Vincent Wai-Sun Wong Manuel Romero-Gomez Kathryn Kersey Georgia Li G. Mani Subramanian Robert P. Myers C. Stephen Djedjos Takeshi Okanoue Michael Trauner Zachary Goodman Stephen A. Harrison |
| Affiliation: | 1. Betty and Guy Beatty Center for Integrated Research, Inova Health System, Falls Church, Virginia;3. Department of Medicine, Center for Liver Diseases, Inova Fairfax Hospital, Falls Church, Virginia;4. Center for Outcomes Research in Liver Disease (COR-LD), Washington, District of Columbia;6. Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle-upon-Tyne, and Newcastle NIHR Biomedical Research Centre, Newcastle-upon-Tyne, United Kingdom;5. Texas Liver Institute, University of Texas Health San Antonio, San Antonio, Texas;7. Hospital Universitario Virgen del Rocio, Sevilla, Spain;12. Gilead Sciences, Inc, Foster City, California;8. Saiseikai Suita Hospital, Suita City, Osaka, Japan;10. Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria;9. Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom |
| Abstract: | |
| Keywords: | NAFLD BMI Physical Function Emotional Utilities APRI AST-to-Platelet Ratio Index BMI body mass index BP Bodily Pain CLDQ-NASH Chronic Liver Disease Questionnaire-NASH DM diabetes mellitus ELF Enhanced Liver Fibrosis F3 bridging fibrosis F4 cirrhosis GH General Health HCC hepatocellular carcinoma HOMA homeostasis assessment model HRQL health-related quality of life MCS Mental Component Summary MELD Model for End-Stage Liver Disease MH Mental Health NASH nonalcoholic steatohepatitis PCS Physical Component Summary PF Physical Functioning PRO patient-reported outcome RE Role Emotional RP Role Physical SF Social Functioning SF-36 Short Form-36 TE transient elastography VT vitality WPAI:SHP Work Productivity and Activity Impairment: Specific Health Problem |
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