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Targeted Integration and High-Level Transgene Expression in AAVS1 Transgenic Mice after In Vivo HSC Transduction with HDAd5/35++ Vectors
Authors:Chang Li  Arpit Suresh Mishra  Sucheol Gil  Meng Wang  Aphrodite Georgakopoulou  Thalia Papayannopoulou  R. David Hawkins  André Lieber
Affiliation:1. Division of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA;2. Division of Hematology, University of Washington, Box 357720, Seattle, WA 98195, USA;3. Department of Pathology, University of Washington, Box 357720, Seattle, WA 98195, USA
Abstract:
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  • Keywords:Corresponding author: André Lieber, Division of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA.  helper-dependent adenovirus  hematopoietic stem cell  targeted integration  AAVS1  CRISPR/Cas9  transgenic mice
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