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Impact of bariatric surgery on heart failure mortality
Authors:Essa M. Aleassa  Zhamak Khorgami  Tammy L. Kindel  Chao Tu  W.H. Wilson Tang  Philip R. Schauer  Stacy A. Brethauer  Ali Aminian
Affiliation:1. Department of General Surgery, Bariatric and Metabolic Institute, Cleveland Clinic, Cleveland, Ohio;2. Department of Surgery, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates;3. Department of Surgery, University of Oklahoma, College of Medicine, Tulsa, Oklahoma;4. Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin;5. Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio;6. Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio;7. Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio
Abstract:BackgroundThe impact of bariatric surgery on discrete cardiovascular events has not been well characterized.ObjectivesTo assess the impact of prior bariatric surgery on mortality associated with heart failure (HF) admission.SettingA retrospective analysis of 2007–2014 Healthcare Cost and Utilization Project—Nationwide Inpatient Sample.MethodsParticipants including 2810 patients with a principal discharge diagnosis of HF who also had a history of prior bariatric surgery were identified. These patients were matched 1:5 with patients who had similar principal diagnoses but no history of bariatric surgery (controls). Propensity scores, balanced on baseline characteristics, were used to assemble 2 control groups. Control group-1 included patients with obesity (body mass index [BMI] ≥35 kg/m2) only. In control group-2, the BMI was considered as one of the matching criteria in propensity matching. Multivariate regression models were utilized to calculate the odds ratio (OR) and 95% confidence interval (CI) of mortality and length of stay (LOS).ResultsWith well-balanced matching, 33,720 (weighted) patients were included in the analysis. In-hospital mortality rates after HF admission were significantly lower in patients with a history of bariatric surgery compared with control group-1 (0.96% versus 1.86%, OR .52, 95% CI .35–0.77, P = .0013) and control group-2 (0.96% versus 1.86%, OR .52, 95% CI .35–0.77, P = .0011). Furthermore, LOS was shorter in the bariatric surgery group compared with control group-1 (4.8 ± 4.4 versus 5.7 ± 5.7 d, P < .001) and control group-2 (4.8 ± 4.4 versus 5.4 ± 6.3 d, P < .001).ConclusionsOur data suggest that prior bariatric surgery is associated with almost 50% reduction in in-hospital mortality and shorter LOS in patients with HF admission.
Keywords:Correspondence: Ali Aminian, M.D., F.A.C.S., F.A.S.M.B.S., Bariatric and Metabolic Institute, Department of General Surgery, Cleveland Clinic, 9500 Euclid Avenue, M61, Cleveland, OH 44195.  Bariatric surgery  National inpatient sample database  Heart failure  Mortality  Length of hospital stay  Survival  Obesity  Heart  Weight loss
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