Quality of life,risk behaviors and depression among carriers of hepatitis C virus and human T-cell lymphotropic virus type 1: a comparative study |
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| Authors: | Ricardo Henrique-Araújo Lucas C. Quarantini André C. Caribé Felipe C. Argolo Ana Paula Jesus-Nunes Mychelle Morais-de-Jesus Adriana Dantas-Duarte Tayne Miranda Moreira Irismar Reis de Oliveira |
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| Affiliation: | 1. Federal University of Bahia, Institute of Health Sciences, Postgraduate Program in Interactive Processes of Organs and Systems, Salvador, BA, Brazil;2. Nova Esperança Medical School, João Pessoa, PB, Brazil;3. Hospital Complex of Infectious Diseases Clementino Fraga, João Pessoa, PB, Brazil;4. Federal University of Bahia, Postgraduate Program in Medicine and Health, Salvador, BA, Brazil;5. Federal University of Bahia, Psychiatry Service, University Hospital (Com-HUPES), Salvador, BA, Brazil;6. Federal University of São Paulo, Postgraduate Program in Psychiatry and Medical Psychology, São Paulo, SP, Brazil |
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| Abstract: | Human T-cell lymphotropic virus type 1 (HTLV-1) has low prevalence rates, but is endemic in some regions of the world. It is usually a chronic asymptomatic infection, but it can be associated with serious neurologic and urinary conditions. Hepatitis C virus (HCV) is broadly spread out worldwide. The majority of these infections have a chronic course that may progress to cirrhosis and hepatocellular carcinoma.ObjectivesTo compare sociodemographic and mental health (risk behaviors, depression, and suicide) aspects, and quality of life among patients with HCV or HTLV-1.MethodsObservational, comparative and cross-sectional study involving outpatients with HCV or HLTV-1 infection. Sociodemographic characteristics, risk behaviors and quality of life were assessed through the questionnaires Mini International Neuropsychiatric Interview – MINI Plus (depression and suicide) and Medical Outcomes Study 36-Item Short-Form Health Survey (quality of life). Univariate and multivariate statistical analyses (hierarchical logistic regression) were conducted.Results143 individuals with HCV and 113 individuals with HTLV-1 infection were included. Males were predominant in the HCV group (68.8%) and females in the HTLV-1 group (71.7%). The frequency of risk behaviors (sexual and drug use) was greater in those with HCV (p < 0.05). A past depressive episode was more common in the HTLV-1 group (p = 0.037). Quality of life was significantly worse in the physical functioning, vitality, mental health, and social functioning domains in those with HTLV-1 (p < 0.05). HTLV-1 infection remained independently associated with worse quality of life in multivariate analysis.ConclusionsRisk behaviors are frequent among those infected with HCV. Additionally, despite HTLV-1 being considered an infection with low morbidity, issues related to mental health (depressive episode) and decreased quality of life are relevant. |
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| Keywords: | Hepatitis C virus Human T-cell lymphotropic virus type 1 Quality of life Risk behaviors Depression Suicide |
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